Gene information
Official symbol IFNGR2
Official full name interferon gamma receptor 2
Gene type protein-coding gene
Chromosome21q22.11
Alias symbolAF-1
Previous symbolIFNGT1
Gene familyFibronectin type III domain containing; Interferon receptors
Resources
Entrez Gene 3460
HGNC HGNC:5440
Ensembl ENSG00000159128
Vega OTTHUMG00000065188
UCSC uc002yrp.4
GO terms: 27 records
GO Description Category LogP Number of genes Detail
GO:0004896 cytokine receptor activity GO Molecular Functions -9.30297759 21 More
GO:0009615 response to virus GO Biological Processes -11.2861143 47 More
GO:0010469 regulation of signaling receptor activity GO Biological Processes -13.5880476 20 More
GO:0022898 regulation of transmembrane transporter activity GO Biological Processes -11.1988499 41 More
GO:0032409 regulation of transporter activity GO Biological Processes -16.9480646 53 More
GO:0032411 positive regulation of transporter activity GO Biological Processes -5.68668981 10 More
GO:0032412 regulation of ion transmembrane transporter activity GO Biological Processes -9.90560995 38 More
GO:0032414 positive regulation of ion transmembrane transporter activity GO Biological Processes -4.25838891 8 More
GO:0034341 response to interferon-gamma GO Biological Processes -10.8524889 26 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0034767 positive regulation of ion transmembrane transport GO Biological Processes -11.2867591 18 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043270 positive regulation of ion transport GO Biological Processes -23.5832054 34 More
GO:0051607 defense response to virus GO Biological Processes -3.02916189 22 More
GO:0098586 cellular response to virus GO Biological Processes -6.52248641 17 More
GO:0099601 regulation of neurotransmitter receptor activity GO Biological Processes -3.10443788 5 More
GO:0140375 immune receptor activity GO Molecular Functions -8.53513203 25 More
GO:0140546 defense response to symbiont GO Biological Processes -3.00647654 22 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904064 positive regulation of cation transmembrane transport GO Biological Processes -10.8655330 17 More
GO:1904783 positive regulation of NMDA glutamate receptor activity GO Biological Processes -6.54368931 4 More
GO:2000273 positive regulation of signaling receptor activity GO Biological Processes -8.61037442 14 More
GO:2000310 regulation of NMDA receptor activity GO Biological Processes -3.92081595 4 More
GO:2001257 regulation of cation channel activity GO Biological Processes -11.2578208 33 More
GO:2001259 positive regulation of cation channel activity GO Biological Processes -4.43623555 7 More
KEGG pathways: 8 records
KEGG Description Category LogP Number of genes Detail
hsa04380 Osteoclast differentiation KEGG Pathway -7.05199617 21 More
hsa04658 Th1 and Th2 cell differentiation KEGG Pathway -5.18694144 15 More
hsa05140 Leishmaniasis KEGG Pathway -12.4439861 14 More
hsa05145 Toxoplasmosis KEGG Pathway -13.6215025 17 More
hsa05168 Herpes simplex virus 1 infection KEGG Pathway -3.99478875 17 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer KEGG Pathway -4.03177682 7 More
hsa05321 Inflammatory bowel disease KEGG Pathway -16.3800424 16 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
interferon gamma-1b binderagonist TdgClinicalTrialChemblInteractions 176184441723963111752352 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NG_007570.2:g.18060G>A genomics acute myocardial infarction[diagnosis] acute myocardial infarction Shalia K et al. Indian J Med Res. 2017
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